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Hypothermic activity of acetaminophen; involvement of GABA(A) receptor, theoretical and experimental studies

OBJECTIVE(S): The mechanism of hypothermia action of acetaminophen (APAP) remains unclear even 125 years after its synthesis. Acetaminophen produces hypothermia. The mechanism of this reduction in core body temperature is not clear but evidence shows that it is not dependent on opioid and cannabinoi...

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Detalles Bibliográficos
Autores principales: Ahangar, Nematollah, Esam, Zohreh, Bekhradnia, Ahmadreza, Ebrahimzadeh, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923466/
https://www.ncbi.nlm.nih.gov/pubmed/27403252