Metallothioneins 1 and 2 Modulate Inflammation and Support Remodeling in Ischemic Cardiomyopathy in Mice

Aims. Repetitive brief ischemia and reperfusion (I/R) is associated with left ventricular dysfunction during development of ischemic cardiomyopathy. We investigated the role of zinc-donor proteins metallothionein MT1 and MT2 in a closed-chest murine model of I/R. Methods. Daily 15-minute LAD-occlusi...

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Detalles Bibliográficos
Autores principales: Duerr, Georg D., Dewald, Daniela, Schmitz, Eva J., Verfuerth, Luise, Keppel, Katharina, Peigney, Christine, Ghanem, Alexander, Welz, Armin, Dewald, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923606/
https://www.ncbi.nlm.nih.gov/pubmed/27403038
http://dx.doi.org/10.1155/2016/7174127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923606/
https://www.ncbi.nlm.nih.gov/pubmed/27403038
http://dx.doi.org/10.1155/2016/7174127

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