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Metallothioneins 1 and 2 Modulate Inflammation and Support Remodeling in Ischemic Cardiomyopathy in Mice

Aims. Repetitive brief ischemia and reperfusion (I/R) is associated with left ventricular dysfunction during development of ischemic cardiomyopathy. We investigated the role of zinc-donor proteins metallothionein MT1 and MT2 in a closed-chest murine model of I/R. Methods. Daily 15-minute LAD-occlusi...

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Detalles Bibliográficos
Autores principales:	Duerr, Georg D., Dewald, Daniela, Schmitz, Eva J., Verfuerth, Luise, Keppel, Katharina, Peigney, Christine, Ghanem, Alexander, Welz, Armin, Dewald, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923606/ https://www.ncbi.nlm.nih.gov/pubmed/27403038 http://dx.doi.org/10.1155/2016/7174127

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