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Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington’s Disease
Within the past decade, there has been increasing interest in the role of tryptophan (Trp) metabolites and the kynurenine pathway (KP) in diseases of the brain such as Huntington’s disease (HD). Evidence is accumulating to suggest that this pathway is imbalanced in neurologic disease states. The KP...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923717/ https://www.ncbi.nlm.nih.gov/pubmed/26397892 http://dx.doi.org/10.3233/JHD-159003 |