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Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin Inhibitors
Experimental evidence suggests that the protein phosphatase calcineurin mediates the action of amyloid-β (Aβ) oligomers, the most toxic amyloid species thought to drive initial cognitive decline in Alzheimer’s disease (AD). However, there is currently no evidence that inhibition of calcineurin could...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923720/ https://www.ncbi.nlm.nih.gov/pubmed/26401556 http://dx.doi.org/10.3233/JAD-150065 |