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Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin Inhibitors

Experimental evidence suggests that the protein phosphatase calcineurin mediates the action of amyloid-β (Aβ) oligomers, the most toxic amyloid species thought to drive initial cognitive decline in Alzheimer’s disease (AD). However, there is currently no evidence that inhibition of calcineurin could...

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Detalles Bibliográficos
Autores principales: Taglialatela, Giulio, Rastellini, Cristiana, Cicalese, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923720/
https://www.ncbi.nlm.nih.gov/pubmed/26401556
http://dx.doi.org/10.3233/JAD-150065