Cargando…

Increased erythrocyte adhesion to VCAM-1 during pulsatile flow: Application of a microfluidic flow adhesion bioassay

Sickle cell disease (SCD) is characterized by microvascular occlusion mediated by adhesive interactions of sickle erythrocytes (SSRBCs) to the endothelium. Most in vitro flow adhesion assays measure SSRBC adhesion during continuous flow, although in vivo SSRBC adhesive interactions occur during puls...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Jennell, Lancelot, Moira, Sarnaik, Sharada, Hines, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923762/
https://www.ncbi.nlm.nih.gov/pubmed/24898561
http://dx.doi.org/10.3233/CH-141847