WISP1-αvβ3 integrin signaling positively regulates TLR-triggered inflammation response in sepsis induced lung injury

We recently noted that the matricellular protein WISP1 contributes to sepsis induced acute lung injury (ALI) via integrin β6. In the current study, we pursued further aspects of WISP1 modulation of TLR signaling in lungs of mice after sepsis and TLR4 mediated release of TNF-α in macrophages. After c...

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Detalles Bibliográficos
Autores principales: Chen, Zhixia, Ding, Xibing, Jin, Shuqing, Pitt, Bruce, Zhang, Liming, Billiar, Timothy, Li, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923866/
https://www.ncbi.nlm.nih.gov/pubmed/27349568
http://dx.doi.org/10.1038/srep28841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923866/
https://www.ncbi.nlm.nih.gov/pubmed/27349568
http://dx.doi.org/10.1038/srep28841

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