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Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

Puberty marks numerous physiological processes which are initiated by central activation of the hypothalamic–pituitary–gonadal axis, followed by development of secondary sexual characteristics. To a large extent, pubertal timing is heritable, but current knowledge of genetic polymorphisms only expla...

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Detalles Bibliográficos
Autores principales: Almstrup, Kristian, Lindhardt Johansen, Marie, Busch, Alexander S., Hagen, Casper P., Nielsen, John E., Petersen, Jørgen Holm, Juul, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923870/
https://www.ncbi.nlm.nih.gov/pubmed/27349168
http://dx.doi.org/10.1038/srep28657