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Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood
Puberty marks numerous physiological processes which are initiated by central activation of the hypothalamic–pituitary–gonadal axis, followed by development of secondary sexual characteristics. To a large extent, pubertal timing is heritable, but current knowledge of genetic polymorphisms only expla...
Autores principales: | Almstrup, Kristian, Lindhardt Johansen, Marie, Busch, Alexander S., Hagen, Casper P., Nielsen, John E., Petersen, Jørgen Holm, Juul, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923870/ https://www.ncbi.nlm.nih.gov/pubmed/27349168 http://dx.doi.org/10.1038/srep28657 |
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