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Potential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin

The transient precorneal retention time and low penetration capacity into intraocular tissues are the key obstacles that hinder the ophthalmic drug delivery of many therapeutic compounds, especially for drugs with poor solubility and permeability. To break the stalemate, N-acetyl-L-cysteine function...

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Detalles Bibliográficos
Autores principales: Liu, Dandan, Li, Jinyu, Pan, Hao, He, Fengwei, Liu, Zhidong, Wu, Qingyin, Bai, Chunping, Yu, Shihui, Yang, Xinggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923878/
https://www.ncbi.nlm.nih.gov/pubmed/27350323
http://dx.doi.org/10.1038/srep28796