Cargando…

Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling

The heart-failure relevant Potassium Channel Interacting Protein 2 (KChIP2) augments Ca(V)1.2 and K(V)4.3. KChIP3 represses Ca(V)1.2 transcription in cardiomyocytes via interaction with regulatory DNA elements. Hence, we tested nuclear presence of KChIP2 and if KChIP2 translocates into the nucleus i...

Descripción completa

Detalles Bibliográficos
Autores principales: Winther, Sine V., Tuomainen, Tomi, Borup, Rehannah, Tavi, Pasi, Antoons, Gudrun, Thomsen, Morten B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923891/
https://www.ncbi.nlm.nih.gov/pubmed/27349185
http://dx.doi.org/10.1038/srep28760