Epigenetic repression of ribosomal RNA transcription by ROCK-dependent aberrant cytoskeletal organization

It is known that ribosomal RNA (rRNA) synthesis is regulated by cellular energy and proliferation status. In this study, we investigated rRNA gene transcription in response to cytoskeletal stress. Our data revealed that the cell shape constrained by isotropic but not elongated micropatterns in HeLa...

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Detalles Bibliográficos
Autores principales: Wu, Tse-Hsiang, Kuo, Yuan-Yeh, Lee, Hsiao-Hui, Kuo, Jean-Cheng, Ou, Meng-Hsin, Chang, Zee-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923894/
https://www.ncbi.nlm.nih.gov/pubmed/27350000
http://dx.doi.org/10.1038/srep28685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923894/
https://www.ncbi.nlm.nih.gov/pubmed/27350000
http://dx.doi.org/10.1038/srep28685

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