Phosphocholine – an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors

We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from human and murine monocytes by a mechanism involving nicotinic acetylcholine receptors (nAChR). Interleukin-1β is a potent pro-inflammatory cytoki...

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Detalles Bibliográficos
Autores principales: Richter, K., Mathes, V., Fronius, M., Althaus, M., Hecker, A., Krasteva-Christ, G., Padberg, W., Hone, A. J., McIntosh, J. M., Zakrzewicz, A., Grau, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923896/
https://www.ncbi.nlm.nih.gov/pubmed/27349288
http://dx.doi.org/10.1038/srep28660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923896/
https://www.ncbi.nlm.nih.gov/pubmed/27349288
http://dx.doi.org/10.1038/srep28660

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