Guanine-rich sequences inhibit proofreading DNA polymerases

DNA polymerases with proofreading activity are important for accurate amplification of target DNA. Despite numerous efforts have been made to improve the proofreading DNA polymerases, they are more susceptible to be failed in PCR than non-proofreading DNA polymerases. Here we showed that proofreadin...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao-Jing, Sun, Shuhui, Xie, Binghua, Hu, Xuemei, Zhang, Zunyi, Qiu, Mengsheng, Dai, Zhong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923904/
https://www.ncbi.nlm.nih.gov/pubmed/27349576
http://dx.doi.org/10.1038/srep28769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923904/
https://www.ncbi.nlm.nih.gov/pubmed/27349576
http://dx.doi.org/10.1038/srep28769

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