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New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit

Thus far, all solved structures of pilin-proteins comprising sortase-assembled pili are from pathogenic genera and species. Here, we present the first crystal structure of a pilin subunit (SpaA) from a non-pathogen host (Lactobacillus rhamnosus GG). SpaA consists of two tandem CnaB-type domains, eac...

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Detalles Bibliográficos
Autores principales: Chaurasia, Priyanka, Pratap, Shivendra, von Ossowski, Ingemar, Palva, Airi, Krishnan, Vengadesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923907/
https://www.ncbi.nlm.nih.gov/pubmed/27349405
http://dx.doi.org/10.1038/srep28664