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New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit
Thus far, all solved structures of pilin-proteins comprising sortase-assembled pili are from pathogenic genera and species. Here, we present the first crystal structure of a pilin subunit (SpaA) from a non-pathogen host (Lactobacillus rhamnosus GG). SpaA consists of two tandem CnaB-type domains, eac...
Autores principales: | Chaurasia, Priyanka, Pratap, Shivendra, von Ossowski, Ingemar, Palva, Airi, Krishnan, Vengadesan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923907/ https://www.ncbi.nlm.nih.gov/pubmed/27349405 http://dx.doi.org/10.1038/srep28664 |
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