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TRAIP regulates replication fork recovery and progression via PCNA

PCNA is a central scaffold that coordinately assembles replication and repair machineries at DNA replication forks for faithful genome duplication. Here, we describe TRAIP (RNF206) as a novel PCNA-interacting factor that has important roles during mammalian replicative stress responses. We show that...

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Detalles Bibliográficos
Autores principales: Feng, Wanjuan, Guo, Yingying, Huang, Jun, Deng, Yiqun, Zang, Jianye, Huen, Michael Shing-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923944/
https://www.ncbi.nlm.nih.gov/pubmed/27462463
http://dx.doi.org/10.1038/celldisc.2016.16