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RIG-I inhibits pancreatic β cell proliferation through competitive binding of activated Src

Nutrition is a necessary condition for cell proliferation, including pancreatic β cells; however, over-nutrition, and the resulting obesity and glucolipotoxicity, is a risk factor for the development of Type 2 diabetes mellitus (DM), and causes inhibition of pancreatic β-cells proliferation and thei...

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Detalles Bibliográficos
Autores principales: Pan, Yi, Li, GuangMing, Zhong, HengGao, Chen, MeiJuan, Chen, TingTing, Gao, LiLi, Wu, HuiWen, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923948/
https://www.ncbi.nlm.nih.gov/pubmed/27349479
http://dx.doi.org/10.1038/srep28914