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High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

Prolonged high fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and diets high in saturated fat are a risk factor for the development of human inflammatory bowel diseases. We hypothesized that HFD-induced endoplasmic reticulum (ER)/oxidative stress occur in intestinal secret...

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Detalles Bibliográficos
Autores principales: Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuív, Páraic Ó., McGuckin, Michael A., Hasnain, Sumaira Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924095/
https://www.ncbi.nlm.nih.gov/pubmed/27350069
http://dx.doi.org/10.1038/srep28990