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The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages

Proinflammatory cytokine production in macrophages involves multiple regulatory mechanisms, which are affected by environmental and intrinsic stress. In particular, accumulating evidence has suggested epigenetic control of macrophage differentiation and function mainly in vitro. SET domain, bifurcat...

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Detalles Bibliográficos
Autores principales: Hachiya, Rumi, Shiihashi, Takuya, Shirakawa, Ibuki, Iwasaki, Yorihiro, Matsumura, Yoshihiro, Oishi, Yumiko, Nakayama, Yukiteru, Miyamoto, Yoshihiro, Manabe, Ichiro, Ochi, Kozue, Tanaka, Miyako, Goda, Nobuhito, Sakai, Juro, Suganami, Takayoshi, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924096/
https://www.ncbi.nlm.nih.gov/pubmed/27349785
http://dx.doi.org/10.1038/srep28845