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The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages
Proinflammatory cytokine production in macrophages involves multiple regulatory mechanisms, which are affected by environmental and intrinsic stress. In particular, accumulating evidence has suggested epigenetic control of macrophage differentiation and function mainly in vitro. SET domain, bifurcat...
Autores principales: | Hachiya, Rumi, Shiihashi, Takuya, Shirakawa, Ibuki, Iwasaki, Yorihiro, Matsumura, Yoshihiro, Oishi, Yumiko, Nakayama, Yukiteru, Miyamoto, Yoshihiro, Manabe, Ichiro, Ochi, Kozue, Tanaka, Miyako, Goda, Nobuhito, Sakai, Juro, Suganami, Takayoshi, Ogawa, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924096/ https://www.ncbi.nlm.nih.gov/pubmed/27349785 http://dx.doi.org/10.1038/srep28845 |
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