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Simple approach for ranking structure determining residues

Mutating residues has been a common task in order to study structural properties of the protein of interest. Here, we propose and validate a simple method that allows the identification of structural determinants; i.e., residues essential for preservation of the stability of global structure, regard...

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Detalles Bibliográficos
Autores principales: Luna-Martínez, Oscar D., Vidal-Limón, Abraham, Villalba-Velázquez, Miryam I., Sánchez-Alcalá, Rosalba, Garduño-Juárez, Ramón, Uversky, Vladimir N., Becerril, Baltazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924125/
https://www.ncbi.nlm.nih.gov/pubmed/27366642
http://dx.doi.org/10.7717/peerj.2136