Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats

BACKGROUND: Hyperhomocysteinemia (HHcy) is associated with inflammation and a rise in the expression of matrix metalloproteinase-9 (MMP-9) in the vascular wall. However, the role of HHcy in the growth and rupture of cerebral aneurysms remains unclear. METHODS: Thirteen-week-old female Sprague-Dawley...

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Detalles Bibliográficos
Autores principales: Korai, Masaaki, Kitazato, Keiko T., Tada, Yoshiteru, Miyamoto, Takeshi, Shimada, Kenji, Matsushita, Nobuhisa, Kanematsu, Yasuhisa, Satomi, Junichiro, Hashimoto, Tomoki, Nagahiro, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924228/
https://www.ncbi.nlm.nih.gov/pubmed/27349749
http://dx.doi.org/10.1186/s12974-016-0634-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924228/
https://www.ncbi.nlm.nih.gov/pubmed/27349749
http://dx.doi.org/10.1186/s12974-016-0634-3

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