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HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells

BACKGROUND: Occurrence and progression of hepatocellular carcinoma (HCC) are associated with hepatitis B virus (HBV) infection. miR-1269b is up-regulated in HCC cells and tissues. However, the regulation of miR-1269b expression by HBV and the mechanism underlying the oncogenic activity of miR-1269b...

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Detalles Bibliográficos
Autores principales: Kong, Xiao-xiao, Lv, Yan-ru, Shao, Li-ping, Nong, Xiang-yang, Zhang, Guang-ling, Zhang, Yi, Fan, Hong-xia, Liu, Min, Li, Xin, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924318/
https://www.ncbi.nlm.nih.gov/pubmed/27349221
http://dx.doi.org/10.1186/s12967-016-0949-y