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Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis

BACKGROUND: Spondyloarthritis (SpA) usually manifests as arthritis of the axial and peripheral joints but can also result in extra-articular manifestations such as inflammatory bowel disease. Proinflammatory cytokine interleukin-17 (IL-17) plays a crucial role in the pathogenesis of SpA. Rebamipide...

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Detalles Bibliográficos
Autores principales: Min, Hong-Ki, Kim, Jae-Kyung, Lee, Seon-Yeong, Kim, Eun-Kyung, Lee, Seung Hoon, Lee, Jennifer, Kwok, Seung-Ki, Cho, Mi-La, Park, Sung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924325/
https://www.ncbi.nlm.nih.gov/pubmed/27350608
http://dx.doi.org/10.1186/s12967-016-0942-5