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Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis
BACKGROUND: Spondyloarthritis (SpA) usually manifests as arthritis of the axial and peripheral joints but can also result in extra-articular manifestations such as inflammatory bowel disease. Proinflammatory cytokine interleukin-17 (IL-17) plays a crucial role in the pathogenesis of SpA. Rebamipide...
Autores principales: | Min, Hong-Ki, Kim, Jae-Kyung, Lee, Seon-Yeong, Kim, Eun-Kyung, Lee, Seung Hoon, Lee, Jennifer, Kwok, Seung-Ki, Cho, Mi-La, Park, Sung-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924325/ https://www.ncbi.nlm.nih.gov/pubmed/27350608 http://dx.doi.org/10.1186/s12967-016-0942-5 |
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