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EphA4‐deleted microenvironment regulates cancer development and leukemoid reaction of the isografted 4T1 murine breast cancer via reduction of an IGF1 signal

EphA4 belongs to the largest family of receptor tyrosine kinases (RTKs). Although EphA4 is highly expressed in the central nervous system, EphA4 has also been implicated in cancer progression. Most of the studies focus on the expression and function in tumor cells. It is unknown whether EphA4‐delete...

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Detalles Bibliográficos
Autores principales: Jing, Xuefeng, Sonoki, Takashi, Miyajima, Masayasu, Sawada, Takahiro, Terada, Nanako, Takemura, Shigeki, Sakaguchi, Kazushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924380/
https://www.ncbi.nlm.nih.gov/pubmed/26923183
http://dx.doi.org/10.1002/cam4.670