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Development and characterization of an in vitro model of colorectal adenocarcinoma with MDR phenotype

The major cause of failure in cancer chemotherapy is the development of multidrug resistance (MDR), and the characterization of biological factors involved in this response to therapy is particularly needed. A doxorubicin‐resistant HCT‐8/R clone was selected from sensitive parental cells and charact...

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Detalles Bibliográficos
Autores principales: Cinci, Lorenzo, Luceri, Cristina, Bigagli, Elisabetta, Carboni, Ilaria, Paccosi, Sara, Parenti, Astrid, Guasti, Daniele, Coronnello, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924386/
https://www.ncbi.nlm.nih.gov/pubmed/27016279
http://dx.doi.org/10.1002/cam4.694