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Enzymatic Macrocyclization of 1,2,3‐Triazole Peptide Mimetics

The macrocyclization of linear peptides is very often accompanied by significant improvements in their stability and biological activity. Many strategies are available for their chemical macrocyclization, however, enzyme‐mediated methods remain of great interest in terms of synthetic utility. To dat...

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Detalles Bibliográficos
Autores principales: Oueis, Emilia, Jaspars, Marcel, Westwood, Nicholas J., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924595/
https://www.ncbi.nlm.nih.gov/pubmed/27397939
http://dx.doi.org/10.1002/ange.201601564