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Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis

OBJECTIVE: Genetic polymorphisms within the HLA region explain only a modest proportion of anti–cyclic citrullinated peptide (anti‐CCP)–negative rheumatoid arthritis (RA) heritability. However, few non‐HLA markers have been identified so far. This study was undertaken to replicate the associations o...

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Detalles Bibliográficos
Autores principales: Viatte, Sebastien, Massey, Jonathan, Bowes, John, Duffus, Kate, Eyre, Stephen, Barton, Anne, Worthington, Jane, Loughlin, John, Arden, Nigel, Birrell, Fraser, Carr, Andrew, Deloukas, Panos, Doherty, Michael, McCaskie, Andrew W., Ollier, William E. R., Rai, Ashok, Ralston, Stuart H., Spector, Tim D., Valdes, Ana M., Wallis, Gillian A., Wilkinson, J. Mark, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924598/
https://www.ncbi.nlm.nih.gov/pubmed/26895230
http://dx.doi.org/10.1002/art.39619