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Age-related changes in the transcriptome of antibody-secreting cells

We analyzed age-related defects in B cell populations from young and aged mice. Microarray analysis of bone marrow resident antibody secreting cells (ASCs) showed significant changes upon aging, affecting multiple genes, pathways and functions including those that play a role in immune regulation, h...

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Detalles Bibliográficos
Autores principales: Kannan, Senthil, Dawany, Noor, Kurupati, Raj, Showe, Louise C., Ertl, Hildegund C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924646/
https://www.ncbi.nlm.nih.gov/pubmed/26967249
http://dx.doi.org/10.18632/oncotarget.7958