Targeting hypoxic response for cancer therapy

Hypoxic tumor microenvironment (HTM) is considered to promote metabolic changes, oncogene activation and epithelial mesenchymal transition, and resistance to chemo- and radio-therapy, all of which are hallmarks of aggressive tumor behavior. Cancer cells within the HTM acquire phenotypic properties t...

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Detalles Bibliográficos
Autores principales: Paolicchi, Elisa, Gemignani, Federica, Krstic-Demonacos, Marija, Dedhar, Shoukat, Mutti, Luciano, Landi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924654/
https://www.ncbi.nlm.nih.gov/pubmed/26859576
http://dx.doi.org/10.18632/oncotarget.7229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924654/
https://www.ncbi.nlm.nih.gov/pubmed/26859576
http://dx.doi.org/10.18632/oncotarget.7229

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