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Targeting hypoxic response for cancer therapy

Hypoxic tumor microenvironment (HTM) is considered to promote metabolic changes, oncogene activation and epithelial mesenchymal transition, and resistance to chemo- and radio-therapy, all of which are hallmarks of aggressive tumor behavior. Cancer cells within the HTM acquire phenotypic properties t...

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Detalles Bibliográficos
Autores principales:	Paolicchi, Elisa, Gemignani, Federica, Krstic-Demonacos, Marija, Dedhar, Shoukat, Mutti, Luciano, Landi, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924654/ https://www.ncbi.nlm.nih.gov/pubmed/26859576 http://dx.doi.org/10.18632/oncotarget.7229

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