ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

Most (80%) of the triple-negative breast cancers (TNBCs) express mutant p53 proteins that acquire oncogenic activities including promoting metastasis. We previously showed that wild-type ERβ (ERβ1) impedes epithelial to mesenchymal transition (EMT) and decreases the invasiveness of TNBC cells. In th...

Descripción completa

Detalles Bibliográficos
Autores principales: Bado, Igor, Nikolos, Fotis, Rajapaksa, Gayani, Gustafsson, Jan-Åke, Thomas, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924664/
https://www.ncbi.nlm.nih.gov/pubmed/26871946
http://dx.doi.org/10.18632/oncotarget.7300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924664/
https://www.ncbi.nlm.nih.gov/pubmed/26871946
http://dx.doi.org/10.18632/oncotarget.7300

Ejemplares similares