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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

Maternal embryonic leucine zipper kinase (MELK), that plays a critical role in maintenance of cancer stem cells (CSCs), is predominantly expressed in various types of human cancer including small cell lung cancer (SCLC). SCLC usually acquires resistance to anti-cancer drugs and portends dismal progn...

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Detalles Bibliográficos
Autores principales: Inoue, Hiroyuki, Kato, Taigo, Olugbile, Sope, Tamura, Kenji, Chung, Suyoun, Miyamoto, Takashi, Matsuo, Yo, Salgia, Ravi, Nakamura, Yusuke, Park, Jae-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924666/
https://www.ncbi.nlm.nih.gov/pubmed/26871945
http://dx.doi.org/10.18632/oncotarget.7297