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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer
Maternal embryonic leucine zipper kinase (MELK), that plays a critical role in maintenance of cancer stem cells (CSCs), is predominantly expressed in various types of human cancer including small cell lung cancer (SCLC). SCLC usually acquires resistance to anti-cancer drugs and portends dismal progn...
Autores principales: | Inoue, Hiroyuki, Kato, Taigo, Olugbile, Sope, Tamura, Kenji, Chung, Suyoun, Miyamoto, Takashi, Matsuo, Yo, Salgia, Ravi, Nakamura, Yusuke, Park, Jae-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924666/ https://www.ncbi.nlm.nih.gov/pubmed/26871945 http://dx.doi.org/10.18632/oncotarget.7297 |
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