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Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells

The oncogenic activation of AKT gene has emerged as a key determinant of the aggressiveness of colorectal cancer (CRC); hence, research has focused on targeting AKT signaling for the treatment of advanced stages of CRC. In this study, we explored the anti-tumorigenic effects of withaferin A (WA) on...

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Detalles Bibliográficos
Autores principales: Suman, Suman, Das, Trinath P., Sirimulla, Suman, Alatassi, Houda, Ankem, Murali K., Damodaran, Chendil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924683/
https://www.ncbi.nlm.nih.gov/pubmed/26883103
http://dx.doi.org/10.18632/oncotarget.7351