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Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells

We previously showed that S-adenosylmethionine-mediated hypermethylation of the PTEN promoter was important for the growth of tamoxifen-resistant MCF-7 (TAMR-MCF-7) cancer cells. Here, we found that the basal expression level of methionine adenosyltransferase 2A (MAT2A), a critical enzyme for the bi...

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Detalles Bibliográficos
Autores principales: Phuong, Nguyen Thi Thuy, Kim, Sang Kyum, Im, Ji Hye, Yang, Jin Won, Choi, Min Chang, Lim, Sung Chul, Lee, Kwang Yeol, Kim, Young-Mi, Yoon, Jeong Hoon, Kang, Keon Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924687/
https://www.ncbi.nlm.nih.gov/pubmed/26418898
http://dx.doi.org/10.18632/oncotarget.5298