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Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells

The potential application of GPNMB/OA as a therapeutic target for lung cancer will require a greater understanding of the impact of GPNMB/OA ectodomain (ECD) protein shedding into tumor tissues. Thus, in this work we characterized GPNMB/OA expression and extent of shedding of its ECD protein while e...

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Detalles Bibliográficos
Autores principales: Oyewumi, Moses O., Manickavasagam, Dharani, Novak, Kimberly, Wehrung, Daniel, Paulic, Nikola, Moussa, Fouad M., Sondag, Gregory R., Safadi, Fayez F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924689/
https://www.ncbi.nlm.nih.gov/pubmed/26883195
http://dx.doi.org/10.18632/oncotarget.7323