Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Endothelial connexin40 (Cx40) contributes to regulate the structure and function of vessels. We have examined whether the protein also modulates the altered growth of vessels in tumor models established in control mice (WT), mice lacking Cx40 (Cx40−/−), and mice expressing the protein solely in endo...

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Detalles Bibliográficos
Autores principales: Alonso, Florian, Domingos-Pereira, Sonia, Le Gal, Loïc, Derré, Laurent, Meda, Paolo, Jichlinski, Patrice, Nardelli-Haefliger, Denise, Haefliger, Jacques-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924695/
https://www.ncbi.nlm.nih.gov/pubmed/26883111
http://dx.doi.org/10.18632/oncotarget.7370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924695/
https://www.ncbi.nlm.nih.gov/pubmed/26883111
http://dx.doi.org/10.18632/oncotarget.7370

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