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Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion
Endothelial connexin40 (Cx40) contributes to regulate the structure and function of vessels. We have examined whether the protein also modulates the altered growth of vessels in tumor models established in control mice (WT), mice lacking Cx40 (Cx40−/−), and mice expressing the protein solely in endo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924695/ https://www.ncbi.nlm.nih.gov/pubmed/26883111 http://dx.doi.org/10.18632/oncotarget.7370 |