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Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer

Castrate-resistant prostate cancer (CRPC) is the fatal form of prostate cancer. Although reactivation of androgen receptor (AR) occurs following androgen deprivation, the precise mechanism involved is unclear. Here we show that the receptor tyrosine kinase, RON alters mechanical properties of cells...

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Detalles Bibliográficos
Autores principales: Batth, Izhar, Yun, Huiyoung, Hussain, Suleman, Meng, Peng, Osumulski, Powel, Huang, Tim Hui-Ming, Bedolla, Roble, Profit, Amanda, Reddick, Robert, Kumar, Addanki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924697/
https://www.ncbi.nlm.nih.gov/pubmed/26872377
http://dx.doi.org/10.18632/oncotarget.7287