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Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors

Ovarian granulosa cell tumors (GCT) are hormonally-active neoplasms characterized, in the adult-subtype, by a mutation in the FOXL2 gene (C134W). They exhibit an indolent course with an unexplained propensity for late recurrence; ∼80% of patients with aggressive, advanced stage tumors die from their...

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Detalles Bibliográficos
Autores principales: Alexiadis, Maria, Chu, Simon, Leung, Dilys, Gould, Jodee A., Jobling, Tom, Fuller, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924709/
https://www.ncbi.nlm.nih.gov/pubmed/26893359
http://dx.doi.org/10.18632/oncotarget.7422