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BK K(+) channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells
Infiltration of the brain by glioblastoma cells reportedly requires Ca(2+) signals and BK K(+) channels that program and drive glioblastoma cell migration, respectively. Ionizing radiation (IR) has been shown to induce expression of the chemokine SDF-1, to alter the Ca(2+) signaling, and to stimulat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924713/ https://www.ncbi.nlm.nih.gov/pubmed/26893360 http://dx.doi.org/10.18632/oncotarget.7423 |