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BK K(+) channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells

Infiltration of the brain by glioblastoma cells reportedly requires Ca(2+) signals and BK K(+) channels that program and drive glioblastoma cell migration, respectively. Ionizing radiation (IR) has been shown to induce expression of the chemokine SDF-1, to alter the Ca(2+) signaling, and to stimulat...

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Detalles Bibliográficos
Autores principales: Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter, Huber, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924713/
https://www.ncbi.nlm.nih.gov/pubmed/26893360
http://dx.doi.org/10.18632/oncotarget.7423

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