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Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth

The Lethal giant larvae (Lgl) gene encodes a cortical cytoskeleton protein, Lgl, and is involved in maintaining cell polarity and epithelial integrity. Previously, we observed that Mgl-1, a mammalian homologue of the Drosophila tumor suppressor protein Lgl, is subjected to degradation via ubiquitin-...

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Detalles Bibliográficos
Autores principales: Lim, Key-Hwan, Suresh, Bharathi, Park, Jung-Hyun, Kim, Young-Soo, Ramakrishna, Suresh, Baek, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924727/
https://www.ncbi.nlm.nih.gov/pubmed/26919101
http://dx.doi.org/10.18632/oncotarget.7581