Cargando…

Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth

The Lethal giant larvae (Lgl) gene encodes a cortical cytoskeleton protein, Lgl, and is involved in maintaining cell polarity and epithelial integrity. Previously, we observed that Mgl-1, a mammalian homologue of the Drosophila tumor suppressor protein Lgl, is subjected to degradation via ubiquitin-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Key-Hwan, Suresh, Bharathi, Park, Jung-Hyun, Kim, Young-Soo, Ramakrishna, Suresh, Baek, Kwang-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924727/ https://www.ncbi.nlm.nih.gov/pubmed/26919101 http://dx.doi.org/10.18632/oncotarget.7581

Ejemplares similares

Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity
por: Ramakrishna, Suresh, et al.
Publicado: (2012)

Ubiquitin Specific Protease 29 Functions as an Oncogene Promoting Tumorigenesis in Colorectal Carcinoma
por: Chandrasekaran, Arun Pandian, et al.
Publicado: (2021)

Ubiquitin-Specific Protease 29 Regulates Cdc25A-Mediated Tumorigenesis
por: Chandrasekaran, Arun Pandian, et al.
Publicado: (2021)

Ubiquitin specific protease 19 involved in transcriptional repression of retinoic acid receptor by stabilizing CORO2A
por: Lim, Key-Hwan, et al.
Publicado: (2016)

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
por: Maertens, Goedele N, et al.
Publicado: (2010)

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
por: Suresh, Bharathi, et al.
Publicado: (2016)

Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation
por: Kaushal, Kamini, et al.
Publicado: (2022)

Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells
por: Rhie, Byung-Ho, et al.
Publicado: (2021)

Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
por: Kaushal, Kamini, et al.
Publicado: (2022)

A Response Regulator Interfaces between the Frz Chemosensory System and the MglA/MglB GTPase/GAP Module to Regulate Polarity in Myxococcus xanthus
por: Keilberg, Daniela, et al.
Publicado: (2012)

MglA/SspA Complex Interactions Are Modulated by Inorganic Polyphosphate
por: Wrench, Algevis P., et al.
Publicado: (2013)

Acute Myeloid Leukemia-Related Proteins Modified by Ubiquitin and Ubiquitin-like Proteins
por: Park, Sang-Soo, et al.
Publicado: (2022)

Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains
por: Harper, Stephen, et al.
Publicado: (2014)

Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells
por: Baek, Dawoon, et al.
Publicado: (2021)

Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatment
por: Huang, Mei-Ling, et al.
Publicado: (2022)

E3 Ubiquitin Ligase APC/C(Cdh1) Negatively Regulates FAH Protein Stability by Promoting Its Polyubiquitination
por: Kaushal, Kamini, et al.
Publicado: (2020)

Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity
por: Miertzschke, Mandy, et al.
Publicado: (2011)

MglC, a Paralog of Myxococcus xanthus GTPase-Activating Protein MglB, Plays a Divergent Role in Motility Regulation
por: McLoon, Anna L., et al.
Publicado: (2016)

Structural characterization of Myxococcus xanthus MglC, a component of the polarity control system, and its interactions with its paralog MglB
por: Kapoor, Srajan, et al.
Publicado: (2021)

Ubiquitin-specific protease 14 modulates degradation of cellular prion protein
por: Homma, Takujiro, et al.
Publicado: (2015)

The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions
por: Zizzari, Ilaria Grazia, et al.
Publicado: (2015)

Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket
por: Grininger, Christoph, et al.
Publicado: (2021)

Substrate specificity of the ubiquitin and Ubl proteases
por: Ronau, Judith A, et al.
Publicado: (2016)

E3 Ubiquitin Ligase APC/C(Cdh1) Regulation of Phenylalanine Hydroxylase Stability and Function
por: Tyagi, Apoorvi, et al.
Publicado: (2020)

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL
por: Scalvini, Laura, et al.
Publicado: (2016)

Deubiquitinating Enzymes as Novel Targets for Cancer Therapies
por: Baek, Kwang-Hyun, et al.
Publicado: (2014)

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain
por: Luna-Vargas, Mark P A, et al.
Publicado: (2011)

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases
por: Pruneda, Jonathan N., et al.
Publicado: (2016)

MglB Fills a GAP in Bacterial Polarity and Motility
por: Sedwick, Caitlin
Publicado: (2010)

MGL Receptor and Immunity: When the Ligand Can Make the Difference
por: Zizzari, Ilaria Grazia, et al.
Publicado: (2015)

Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders
por: Kitamura, Hiroshi
Publicado: (2023)

Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson’s disease
por: Park, Ga Hyun, et al.
Publicado: (2021)

The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS
por: Honn, Marie, et al.
Publicado: (2012)

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells
por: Pirro, Martina, et al.
Publicado: (2018)

Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption
por: Gopalappa, Ramu, et al.
Publicado: (2018)

Protein Degradation and the Pathologic Basis of Phenylketonuria and Hereditary Tyrosinemia
por: Sarodaya, Neha, et al.
Publicado: (2020)

Ubiquitin-Specific Proteases: Players in Cancer Cellular Processes
por: Cruz, Lucas, et al.
Publicado: (2021)

Emerging Roles of Ubiquitin-Specific Protease 25 in Diseases
por: Zhu, Wenjing, et al.
Publicado: (2021)

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system
por: Xu, Daichao, et al.
Publicado: (2015)

Ubiquitin-Specific Protease 4 Inhibits Mono-Ubiquitination of the Master Growth Factor Signaling Kinase PDK1
por: Uras, Iris Z., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7m1kc42t5ju94tki9p89v9tv77