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Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation

B-cell specific moloney leukemia virus insertion site 1 (Bmi-1) gene plays important roles in gastric cancer, but the epigenetic regulatory mechanism by microRNA (miRNA) and the functional significance of Bmi-1 inhibition in gastric cancer remains elusive. In this study, we systematically investigat...

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Detalles Bibliográficos
Autores principales: Wu, Changping, Zheng, Xiao, Li, Xiaodong, Fesler, Andrew, Hu, Wenwei, Chen, Lujun, Xu, Bin, Wang, Qi, Tong, Anthony, Burke, Stephanie, Ju, Jingfang, Jiang, Jingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924733/
https://www.ncbi.nlm.nih.gov/pubmed/26894855
http://dx.doi.org/10.18632/oncotarget.7392