Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

Transmembrane mucins (TMs) are restricted to the apical surface of normal epithelia. In cancer, TMs not only are over-expressed, but also lose polarized distribution. MUC16/CA125 is a high molecular weight TM carrying the CA125 epitope, a well-known molecular marker for human cancers. MUC16 mRNA and...

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Detalles Bibliográficos
Autores principales: Morgado, Micaela, Sutton, Margie N., Simmons, Mary, Warren, Curtis R., Lu, Zhen, Constantinou, Pamela E., Liu, Jinsong, Francis, Lewis LW., Conlan, R. Steven, Bast, Robert C., Carson, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924758/
https://www.ncbi.nlm.nih.gov/pubmed/26918940
http://dx.doi.org/10.18632/oncotarget.7652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924758/
https://www.ncbi.nlm.nih.gov/pubmed/26918940
http://dx.doi.org/10.18632/oncotarget.7652

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