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APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

CD95, a member of the death receptor family initiates a caspase-dependent apoptosis, when activated by its ligand CD95L, thought to negatively regulate erythrocyte production in the bone marrow. We have previously shown that CD95 is overexpressed in two thirds of patients with a lower risk myelodysp...

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Detalles Bibliográficos
Autores principales: Raimbault, Anna, Pierre-Eugene, Cecile, Rouquette, Alexandra, Deudon, Celine, Willems, Lise, Chapuis, Nicolas, Mathis, Stephanie, Kunz, Claudia, Fricke, Harald, Kosmider, Olivier, Bardet, Valerie, Fontenay, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924760/
https://www.ncbi.nlm.nih.gov/pubmed/26910909
http://dx.doi.org/10.18632/oncotarget.7469